| 세션명 | 콜로이드 및 분자조립 부문위원회 (II) |
|---|---|
| 발표장 | 제3회장 |
| 논문코드 | 2L3-6 |
| 발표일 | 2021-10-22 |
| 발표시간 | 15:15-15:40 |
| 논문제목 | Dynamic Assemblies of DNA Block Copolymers |
| 발표자 | 박소정 |
| 발표자 소속 | 이화여자대학교 |
| 저자 | 박소정†, Chan-Jin Kim, Shine K. Albert |
| 소속 | 이화여자대학교 |
| 논문초록 | Here, we present the rational design and fabrication of unusual low-dimensional DNA nanostructures through programmable and sequence-specific peptide interactions. Unlike prototypical DNA block copolymers, which typically form simple spherical micelles, DNA-b-poly(amino acid) assemble into various low-dimensional structures such as nanofibers, ribbons, and sheets through controllable amino-acid interactions. DNA-b-poly(amino acid) assemblies can undergo protease-induced fiber-to-sheet shape transformations, where the morphology change is dictated by the type of enzymes and amino acid sequences. Furthermore, we have demonstrated that unique Janus 2D DNA assemblies can be fabricated by the highly directional peptide self-assembly. The peptide-based self-assembly reported here provides a programmable approach to fabricate dynamic DNA assemblies with unusual low-dimensional structures. |
THE POLYMER SOCIETY OF KOREA